A clinical case of recurrent Clostridium difficile-associated diarrhea in a child

Abstract

Clostridium difficile is the most important infectious aetiology of antibiotic-associated diarrhea. Today, in the era of pandemics and numerous epidemics that have faced the humanity, antibiotic therapy is one of the most common medical practices. However, the careless use and irrational prescription of antibiotics increase the risk of their negative impact on the human body and steadily approach antibiotic resistance. American Academy of Pediatrics reports an increase in the incidence of Clostridium difficile infection in children; a wide spectrum of disease severity can occur, ranging from asymptomatic carriage to severe recurrent diarrhea. Annually 20 thousand cases of Clostridium difficile infection are registered among patients in the pediatric cohort аccording to the American Academy of Pediatrics. The relevance of the topic is due to the increase in the incidence of Clostridium difficile-associated diarrhea, which is a result of irrational antibiotic therapy.