Selection of excipients for the development of a cream with liquid extract of olive leaves

Abstract

The liquid extract derived from olive leaves could serve as a promising component for the formulation of topical medications targeting herpes simplex virus type 1 (HSV-1). Literature contains comparisons of the antiherpetic effects between a microemulsion of olive leaf extract, the pure extract, and acyclovir, which is the standard treatment choice. Research indicates that the microemulsion enhances the effectiveness of liquid olive leaf extract against the HSV type-1 virus when juxtaposed with the pure extract, and it shows efficacy similar to that of the control drug