Hygienic substantiation of necessity for monitoring in the environmental objects of SDHI fungicides considering their possible impact on the thyroid gland

Abstract

Despite their popularity and widespread use, pesticides pose a serious risk to human health not only when mixing and applying pesticides or working in cultivated fields, but in the consumption of food and water containing pesticide residues. The purpose was hygienic substantiation of necessity for monitoring in the environmental objects of SDHI fungicides considering their possible impact on the thyroid gland. Materials and methods of research. To test the proposed selection criteria for hygienic monitoring of pesticides that affect the thyroid gland, we evaluated 4 new SDHI fungicides from the chemical class of pyrazolecarboxamides (isopyrazam, pentiopyrad, sedaxan, fluxapyroxad). Results and discussion. Based on the results obtained, all studied compounds are assigned to the second pesticide group, hygienic monitoring of which is desirable but not required. This is due, on the one hand, to their low toxicity, to the other, to low environmental sustainability. Conclusion. It was shown, that compared to other classes of pesticides, the studied are much less dangerous in terms of groundwater contamination.