Clinical characteristics of stem cell application in the surgical management of post-traumatic and trophic skin defects. Literature review

Abstract

Chronic post-traumatic and trophic skin defects present a significant clinical challenge, particularly in the context of ischemia, infection, diabetic angiopathy and neuropathy, or severe traumatic injuries. Conventional treatments such as debridement, skin grafts, and local or free flaps often fail to achieve durable healing, thereby increasing interest in regenerative technologies.