Formulation of modern requirements for the quality of dietary supplements containing theobromine

Abstract

The increasing consumption of dietary supplements containing biologically active substances has raised significant concerns regarding their quality, safety, and regulatory control. Theobromine, a naturally occurring methylxanthine widely used in functional and stimulant dietary supplements, exhibits pharmacological activity affecting the central nervous, cardiovascular, and metabolic systems. Despite its growing application, unified and scientifically substantiated quality requirements for dietary supplements containing theobromine remain insufficiently developed, particularly within the Ukrainian regulatory framework. This creates potential risks related to inconsistent dosing, inaccurate labeling, and inadequate quality control. Therefore, the development of modern quality requirements and control approaches for dietary supplements containing theobromine is highly relevant in the context of harmonization of national regulations with European standards and ensuring consumer safety.