Assessment of splenic vascular hemodynamics in patients with established portal hypertension and splenomegaly

Abstract

The development of portal hypertension in liver cirrhosis is accompanied by fundamental changes in splanchnic circulation, where the role of the spleen transforms from a passive venous reservoir into an active driver of hemodynamic disturbances. In the present study, based on a comprehensive clinical and instrumental examination of 90 individuals, including 47 patients with liver cirrhosis and established splenomegaly (study group) and 43 practically healthy volunteers (control group), Doppler ultrasonography demonstrated the presence of a pronounced hyperdynamic syndrome in the splenic artery basin.