Prevalence of health care-associated infections and antimicrobial resistance of the responsible pathogens in Ukraine: Results of a multicenter study (2014-2016)

Abstract

Background : The aim of this study was to obtain the first national estimates of the current prevalence and incidence and death of health care - associated infections (HAIs) of all types in acute care hospitals in Ukraine. Methods : prospective surveillance was conducted from January 2014 to December 2016 in 17 hoospitals . surveillance cas definitions were derived from the center for Disease control and preventions National Healthcare safety Nwtwork HAI case definitions . Some antimicrobial susceptibility tests used Kirby-Bauer antibiotic testing . Results : Of 97,340 patients 10,986 (11.3%) HAIs were observed .The most frequntly reported HAI typs were surgical site infections (60%) , respirtory tract infections (pneumonia and lower respiratory tract, (18.4%), bloodstream infections (10.2%),and urinary tract infections (9.5%).Death during jhospitalization was re[prted in 9.7% of HAIcases . The most common orgnism reported was escherichia coli .accounting for 21.8% of all organisms ,followed by staphylococcus aureus (18,4%) , Enterpcpccus spp (15.7%),and pseudomonas aeruginosa (12.4%).Antimicarobial resistance amog the isolates associated with HAIs showed that 42.1% and 3.6% of cogulase-negative staphylococcus spp isolates were b-lactam (oxacillin) - and glycopepitide (teico-planin)-resistant ,respectively .Meyicillimn resistance was reported in 39.2% of s aureus isolats. Conelusions/ : HAIs and increasing antimicrobial resistance present a significant burden to the Ukraine hospital system . Infection control priorities in hospitals should include preventing surgical site infections .respiratory tract infections (which also include PNEU and LRTI) .bloodstream infections and urinary tract infections,as well preventing infections due to antimicrobial-resistant pathogens. 2019 Association for professionals in infection control and Epidemiology .inc ,Published elsevier inc, all rights reseved .