Correlation Of Intracardiac Hemodynamics Indicators With Von Willebrand Factor – Marker Of Endothelial Dysfunction In Patients With Coronary Artery Disease Combined With Coronavirus Disease (Covid-19)

Abstract

The research aims to establish the relationship between indicators and the role of endothelial dysfunction in the pathogenesis of various conditions. The clinical observation method was used, and data such as symptoms, medical history, and laboratory and instrumental studies were collected. The study revealed an increased activity of von Willebrand factor (vWF) in the majority of patients. When comparing groups of patients depending on the presence of concomitant coronavirus disease, it was found that the highest level of vWF was observed in patients with coronary heart disease in combination with coronavirus disease, a lower level in patients with coronavirus disease alone, and the lowest level in patients with chronic coronary heart disease.