Modification of the hplc technique for studing the purity of the chlorhexidine substance as a representative of a number of bis-(chlorophenyl)-(imidodicarbamide-diamide)-s

Abstract

Chlorhexidine is a dangerous drug, therefore, quality control of this drug is important to protect the health and life of patients. Chlorhexidine is a multifunctional organic compound. During the synthesis of chlorhexidine, by-products, unacceptable impurities can be formed - accompanying substances or related substances, which will affect the quality of the substance. Therefore, it is important to introduce modern instrumental methods into the pharmaceutical analysis of the chlorhexidine substance, in addition to the methods recommended by Pharmacopoeias, to improve the quality of the analysis.