Features of maintaining patients with chronic hepatitis C in the background of non-alcoholic fatty illness of a liver

Abstract

Concomitant of chronic hepatitis C and non-alcoholic fatty liver disease is characterized by more sever course of the disease, more rapid progression of fibrosis and lower efficacy of specific antiviral treatment. Lipoic acid plays an important role in different physiological processes and possesses potent antioxidant activity, causing reduction of adipose degeneration of hepatocytes and activation of liver metabolic function, also it decrease levels of cholesterol and saturated fatty acids in blood, activates synthesis of glucose and proteins in the liver. Lipoic acid improves carbohydrate metabolism by activation of glucose utilization and reduction of insulin resistance.