Mutually aggravating complications in the development of hepatorenal syndrome in decompensated portal hypertension

Abstract

Hepatorenal syndrome (HRS) developing in the setting of decompensated portal hypertension (PH) is characterized by progressive renal failure, elevated serum creatinine levels, and worsening oliguria. HRS occurs in approximately one-third of patients with Child-Pugh class C liver cirrhosis. The purpose was to optimize early diagnosis and treatment, as well as to identify risk factors for the development of HRS and associated mortality.