Indicators Of Dental Health And Local Immunity In Young Adults Who Have Suffered From Coronavirus Infection

Abstract

The aim: To determine the dental status and state of local immunity in young adults who have su ered from the coronavirus disease. Materials and methods: The main group consisted of 30 people aged 20-22 years, who su ered from the coronavirus infection Covid19 6.1±1.2 months ago. The comparison group included 20 people who did not have a coronavirus infection. The control group consisted of 35 people, randomized by age and sex, who did not have signs of caries and periodontal tissue disease and did not have coronavirus disease. All patients were examined for dental status and local immunity. Results: The analysis of indicators of dental status revealed the possibility of the existence of a relationship between the signs of acute SARS-Cov2 viral infection and the development of caries and periodontal tissue diseases. Signi cant changes in the local immunity of the oral cavity were found in the examined patients, which had a pathogenetic in uence on the development and progression of caries and periodontal tissue diseases: a signi cant increase in the level of Ig G, as well as a probable decrease in the concentration of SIg A relative to the comparison group, a probably higher normative value of pathogenic small- and medium-molecular CICs with a signi cant decrease in the level of physiological large-sized CICs relative to the comparison group, a decrease in the content of anti-in ammatory IL-4, as well as increased concentration of pro-in ammatory cytokines. Conclusions: Young adults who have su ered a coronavirus infection during the last 6 months have signi cantly higher caries prevalence, bleeding index, PMA index and hygiene index, halitosis, which indicates deeper tissue damage and tooth pathology with the formation of dentition defects than in the comparison group. Indicators of local immunity of the oral uid have a deep and speci c character.