Будь ласка, використовуйте цей ідентифікатор, щоб цитувати або посилатися на цей матеріал: http://ir.librarynmu.com/handle/123456789/7768
Повний запис метаданих
Поле DCЗначенняМова
dc.contributor.authorVasylchenko, V. S.-
dc.contributor.authorKorol, L. V.-
dc.contributor.authorKuchmenko, O. B.-
dc.contributor.authorStepanova, N. M.-
dc.date.accessioned2023-05-29T07:33:36Z-
dc.date.available2023-05-29T07:33:36Z-
dc.date.issued2020-
dc.identifier.urihttp://ir.librarynmu.com/handle/123456789/7768-
dc.description.abstractAn excess of free radicals accompanies the development of renal pathologies and causes numerous concomitant complications and syndromes. The most common of these are cardiometabolic syndromes in patients with chronic kidney disease. Therefore, the purpose of the study was to determine the activity of paraoxonase-1 and myeloperoxidase, which are associated with indicators of high-density lipoproteins content and oxidative stress in the blood of patients with the chronic stage of kidney disease. The activity of the enzymes, thiobarbiturate-active products concentration and transferrin, ceruloplasmin, thiol compounds content were determined in the blood of patients with chronic kidney disease. The oxidative status was shown to be changed. Thus, myeloperoxidase activity, the content of oxidized proteins and the concentration of thiobarbiturate-positive components were increased, while the activity of the antioxidant enzyme paraoxonase-1, the content of transferrin, ceruloplasmin and thiol compounds were decreased. The ratio of myeloperoxidase paraoxonase-1 activities was progressively increased up to 9-fold, indicating the presence of cardiovascular complications in patients. The data obtained allowed to extend the range of indicators for monitoring the development of cardiometabolic disorders in the progression of chronic kidney diseasuk_UA
dc.subjectoxidative status, paraoxonase-1, myeloperoxidase, chronic kidney disease.uk_UA
dc.titleThe oxidative status in patients with chronic kidney diseaseuk_UA
dc.typeArticleuk_UA
Розташовується у зібраннях:Наукові публікації кафедри внутрішньої медицини №3

Файли цього матеріалу:
Файл Опис РозмірФормат 
Vasylchenko_5_20.pdf1,02 MBAdobe PDFПереглянути/Відкрити


Усі матеріали в архіві електронних ресурсів захищені авторським правом, всі права збережені.