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Назва: The role of enteroviruses in the development of ischemic stroke and its outcomes
Інші назви: THE ROLE OF ENTEROVIRUSES IN THE DEVELOPMENT OF ISCHEMIC STROKE AND ITS OUTCOMES
Автори: Turchyna, N.
Cherenko, T.
Andriushkova, N.
Melnyk, V.
Kuzminska, O.
Heletiuk, Y.
Ключові слова: Ishemic stroke
neurological deficit
enteroviruses
Дата публікації: 2022
Видавництво: Wiadomosci Lekarskie
Серія/номер: VOLUME LXXV;ISSUE 10
Короткий огляд (реферат): The aim. To study the role of enteroviruses (EV) in the development of ischemic stroke and its outcome. Materials and methods. The main group (MG) included 72 patients with acute cerebrovascular disorders were examined using the National Institutes of Health Stroke Scale and Barthel Index. The comparison group (CG) included 35 patients without cerebrovascular disease. Viruses were isolated from patients’ sera and identified in neutralization test. EV genomes were detected in polymerase chain reaction (PCR). Serological diagnosis was performed by enzyme-linked immunosorbent assay. Results. EV genomes were more frequently detected in the patients’ sera in MG than in CG (23.6 ± 5.9% and 2.9 ± 2.8%, p <0.05). The greater level of neurological deficits was in patients with positive PCR test results comparatively with patients with negative PCR test results (11.76 ± 0.31 and 10.97 ± 0, 27, p = 0.040). The regression of neurological deficit during the treatment was a worse in patients with positive PCR test results and presence of specific IgG compared with patients with positive PCR test results and absence of specific IgG (11.2 ± 2.6% and 19.6 ± 2.4%, p = 0.031). Conclusions. The trigger role of EV in the development of IS is established. PCR is recommended for diagnosis of EV in patients with IS.
URI (Уніфікований ідентифікатор ресурсу): http://ir.librarynmu.com/handle/123456789/6757
ISSN: 0043-5147
Розташовується у зібраннях:Наукові публікації кафедри гігієни харчування та нутріціології

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