The Gastrointestinal Motility in Rats at First Trimester of Pregnancy

Abstract

The aim of the study was to investigate the spontaneous and stimulated motility of stomach and colon in rats on different days of pregnancy. Gastrointestinal motility was recorded by the balloon graphic method on the anesthetized rats. It was established that in pregnant rats amplitude of spontaneous and stimulated by carbachol contractions in stomach and colon was decreased on the 3rd, 4th, 5th and 7th day of pregnancy. In pregnant rats index of spontaneous and stimulated by carbachol gastric motility was diminished on the all days of investigations. Index of spontaneous motor activity of colon on the 3rd day of pregnancy was not statistically significantly different from control but on the 4th, 5th and 7th day of pregnancy index of spontaneous motor activity of colon was reduced. . In pregnant rats index stimulated by carbachol colon motility was diminished on the all days of investigations.