Двостулковий аортальний клапан: особливості утворення кальцинатів і патоморфологічні зміни структури клапана

Abstract

The problem of aortic valve calcinosis in patients with bicuspid aortic valve is discussed. The main pathogenic mechanisms of aortic valve calcinosis as well as its pathomorphological pattern are presented. Hyalinosis, mucoidal changes of basic substance of connective tissue are proved to be main pathohistological changes in bicuspid aortic valve. Calcinosis of aortic valve develops in some patients and therefore pathogenesis of its development require further research