Clinical and morphological substantiation of eliminating of the alveolar bone defects using bioactive long-acting composite “medical glue”

Abstract

At the present stage periradicular chronic inflammatory lesions contribute to the development of odontogenic cysts of jaws and is a leading factor in the partial or total loss of teeth, which leads to changes in the morphology of the alveolar bone of the jaws and adjacent tissues with the formation of bone defects. The purpose of this study was to substantiate of eliminating of the alveolar bone defects using bioactive long-acting composite “Medical Glue”. The study involved 42 patients (w-15, m-27) with radicular cysts of the jaws, an average age was 33.8 ± 9.1years. Additional method of study was computed tomography (CT) with the determination of the size of lesions of bone tissue, an X-ray density assessment of the bone tissue in the cystic defect on the Hounsfield index (HU). Аccording to the density of bone regenerate on 12 months after the operation, this figure was 369.2 ± 47.7 units HU (p = 0.38 versus 370.8 ± 84.7 units HU in a blood clot group), indicating a compliance of terms and phases of material`s biodegradation and reparative osteogenesis, its biocompatibility and efficacy.