Development of modern quality requirements for a dietary supplement containing silymarin

Abstract

Silymarin is a complex of biologically active flavonolignans derived from Silybum marianum, widely used in dietary supplements intended to support liver function and detoxification processes. Due to its antioxidant, anti- inflammatory, and membrane-stabilizing properties, silymarin-containing products are in high demand and are extensively represented on the pharmaceutical and consumer markets. However, dietary supplements in Ukraine are regulated as food products rather than medicinal products, which results in limited requirements for standardization, identification, and quantitative determination of active substances.