Studing the impact of COVID -19 on the progression of metabolic, neuroendocrine disorders and some immunological changes in women with acne

Abstract

Acne is a multifactorial chronic inflammatory disease with primary damage to the pilosebaceous unit and the polymorphic clinical manifestations associated with overproduction of sebaceous glands, pathological desquamation of the sebaceous epithelium of the sebum follicles, activation of saprophytic, conditionally pathogenic microorganisms, and psychoemotional disorders. This is undoubtedly one of the most common dermatoses in clinical practice, accounting for 20—25 % of dermatology consultations. Today, especially in wartime, acne vulgaris remains a socially important problem in approximately half of patients with psychoemotional disorders, mainly of a depressive and anxiety associated nature with a sharp decrease in the quality of life of patients.