Менеджмент ризиків ліко-пов’язанних проблем при застосуванні фосфоміцину у вагітних жінок із інфекцією сечовивідних шляхів

Abstract

Although the pace of introduction of new classes of antibiotics to the market is limited, some older drugs, such as fosfomycin, may still provide a temporary solution to the resistance problem because they have proven effective against common pathogens. The most commonly used antimicrobials in susceptibility testing conducted by clinical laboratories were nalidixic acid, pipemidic acid, cefadroxil, nitrofurantoin, amoxicillin, ampicillin, sulfasalazine, ciprofloxacin, norfloxacin, and levofloxacin, many of which are contraindicated in pregnant women. The susceptibility of isolated bacteria to fosfomycin was 89%, suggesting that it may be an effective, safe, and convenient therapeutic option for the treatment of uncomplicated UTIs during pregnancy.