Application of bacteriophages against multidrug-resistant strains of klebsiella pneumoniae

Abstract

The emergence of antimicrobial-resistant microorganisms poses a serious global public health challenge. Klebsiella pneumoniae is among the most common pathogens responsible for healthcare-associated infections, particularly in critically ill patients. The prevalence of multidrug-resistant (MDR) K. pneumoniae has increased dramatically worldwide over recent decades, presenting an urgent threat to public health. In the absence of effective treatments for severe bacterial infections caused by antibiotic-resistant strains, bacteriophages represent a targeted and promising adjunct – and in some cases, an alternative – to conventional therapy.