Study of factors that affect the stability of intraocular pressure after surgical antiglaucoma intervention in patients with primary open-angle glaucoma

Abstract

Summary. Primary open-angle glaucoma is a multifactorial chronic progressive neurodegenerative disease associated with characteristic structural damage to the optic nerve and associated visual dysfunction, in which intraocular pressure is a key factor. A number of studies in recent years have shown that the number of necessary repeated surgical interventions in glaucoma patients reaches more than 50%. However, to date, the pathogenetic mechanisms that lead to the overgrowth of the channels formed during the operation for the outflow of ocular fluid have not been fully elucidated, and the development and implementation of modern devices (valves) also does not solve the problem. The purpose of our work was to analyze and study risk factors that may affect the frequency of intraocular pressure decompensation in the postoperative period during antiglaucoma interventions and, accordingly, the rapid progression of glaucomatous optic neuropathy.