Personalization Of Surgical Tactics For The Treatment Of Patients With Non-Resectable Pancreatic Head Cancer

Abstract

Due to the late diagnosis, up to 80% of patients with cancer of the head of the pancreas undergo only palliative surgical treatment in order to eliminate complications: obstructive jaundice and duodenal stenosis by a tumor through hepaticojejunostomy surgery or transpapillary prosthetics of the common bile duct with self-expanding metal stents (SEMS)[1]. Disadvantages of open operations are a high frequency of postoperative complications and mortality, and transpapillary stenting – obstruction of up to 40% of stents 6-8 years after their implantation. When using modern polychemotherapy, the survival rate of patients exceeds a year, when the drainage function of stents is impaired, and surgical shunts function without complications. Therefore, it is relevant to personalize the choice of treatment tactics for patients.