Histological peculiarities of nasal cavity mucosa in patients with deviated nasal septum and postnasal drip syndrome

Abstract

Nasal congestion is one of the most common complaints in otolaryngology. It is mostly caused by deviated nasal septum. Anatomic changes in the deviated nasal septum significantly deteriorate the function of the upper airways. The study group includes 45 patients with the deviated nasal septum, and with complaints about difficult nose breathing and feeling of postnasal drip. A control group of 29 people with deviated nasal septum, without postnasal drip. The studies revealed that the nasal mucosa of people in control group has standard anatomy characteristics, with slight variations. The respiratory epithelium with ciliary, goblet and intercalated calls in thin basal membrane was clearly distinguished. The lamina propria contained terminal mucosal glands parts and blood lacunae. The study results evidence that deviation of the nasal septum leads to specific histopathological changes in the nasal mucosa. These changes are significantly different on both sides of the nasal septum