http://ir.librarynmu.com/handle/123456789/6566 Sun, 12 Apr 2026 04:54:23 GMT 2026-04-12T04:54:23Z http://ir.librarynmu.com/handle/123456789/6909 Название: Амінокислоти крові як предиктори життєзагрозливих аритмій у хворих з ішемічною хворобою серця із супутньою інсулінорезистентністю Авторы: Лизогуб, В. Г.; Бєлікова, Ю. О.; Галіч, В. М.; Michelle, A.; Шульга, І. В. Sat, 01 Jan 2022 00:00:00 GMT http://ir.librarynmu.com/handle/123456789/6909 2022-01-01T00:00:00Z http://ir.librarynmu.com/handle/123456789/6908 Название: The relationship of the ratio taurine/alanine in serum and indicators of heart rate variability in patients with postinfarction cardiosclerosis and diabetes mellitus type 2 Авторы: Belikova, J. Краткий осмотр (реферат): The aim of the article : to determine the relationship of the ratio taurine/alanine (Tau/Ala) serum indicators of heart rate variability (HRV) in patients with postinfarction cardiosclerosis (PICS) and diabetes mellitus type 2 (DM 2). Materials and methods: we examined 87 patients with PICS and DM 2 – 50 women and 37 men, median age of the patients was 65.2 years (microtile interval 61-69 years). Amino acids were determined and the ratio between them. According to the results of Holter ECG monitoring (of HMCG) evaluated HRV. Results: in patients with PICS compared with healthy individuals observed a significant decrease in the blood levels of Tau/Ala (at 51.01%, p<0.001). The presence of comorbid diabetes is accompanied by more significant decrease in Tau/Ala (for the accounting period 82.22%, p<0.001) compared to healthy individuals. Between Tau/Ala and SDNN, LF, TP, VLF power of communication has been high, between Tau/Ala and RMSSD, HF, pNN 50.%, ULF, – moderate strength. Conclusions: the lower values of Tau/Ala in the blood of patients Pxs diabetes compared with patients without disorders of carbohydrate metabolism, accompanied by a decrease in spectral and temporal parameters of HRV, but that does not mean a causal relationship, may be associated with pathogenetic mechanisms of disorders of carbohydrate metabolism and requires further research. Tue, 01 Jan 2019 00:00:00 GMT http://ir.librarynmu.com/handle/123456789/6908 2019-01-01T00:00:00Z http://ir.librarynmu.com/handle/123456789/6904 Название: Features of Amino Acid Composition of Blood in Post-Infarction Patients with Impaired Carbohydrate Exchange and Its Interconnection with Cardiovascular Risk Factors Авторы: Bielova, R.; Kuzminets, A.; Lavrenchuk, I.; Ivan, N.; Kumar, N.; Masalawala, M.; Suraj, S.; Chand, R. Краткий осмотр (реферат): Amino acids (AA) are important predictors of ischemic changes in the myocardium and insulin resistance. The purpose of this study is to learn serum AA in patients withpostinfarction cardiosclerosis (PICS) in combination with diabetes mellitus type 2 (DM) and without impaired carbohydrate metabolism, as well as the relationship of AA with indicators of carbohydrate and lipid metabolism as cardiovascular risk (CVR) factors, which may allow using AA as predictors of cardiovascularcomplications. 31 patients with PICS and concomitant DM were selected for the study, which formed the main group (MG). The comparison group (CG) included 27 patients with PICS without DM. Patients with PICS andDM showed a statistically significant increase in the total concentration of AA compared with the CG–by 24.91% (p<0.05) andin the concentration of branched-chain amino acids (BCA) -isoleucine -by 28,39%, leucine-by 41.11% (p<0.001), valine–by 34.1% (p<0.05); lysine concentration–by 11.8% (p<0.05), aspartate–by 17.3% (p <0.001), glutamate–by 11.4% (p<0.05).In patients of the MG there was a significant decrease in the concentration of taurine, arginine, methionine, glycine: by 11.3% (p<0.05), 18,1% (p<0.05), 7.7% (p<0.001), 10.12% (p<0.001), respectively, compared with patients with PICS without impaired carbohydrate metabolism. According to the results of this analysis, the average strength of the inverse correlations of AA with the parameters of lipid metabolism: between taurine and very low-densitycholesterol (VLDL) (r= -0.54; p<0.05), total cholesterol (r=-0.52; p>0.05);between methionine and VLDL (r =-0.62; p<0.05) and ApoB/ApoA1 (r = -0.59; p<0.05).The average strength of the correlation of AA with carbohydrate metabolism was also established: inverse–Tau with HbA1c (r = -0.55; p <0.05), HOMA index (r=-0.45; p<0.05), insulin (r=-0.41; p<0.05);methionine with HOMA index (r=-0.62; p<0.05), and insulin (r=-0.55; p<0.05).Direct correlations of medium strength were found for ARL and Ala (r=0.56 and r=0.55; p <0.05). The presence of correlations between CVR indicators and the content of individual blood AAs suggests the possibility of using AAs as prognostic markers of fatal cardiovascular events and requires further research. Fri, 01 Jan 2021 00:00:00 GMT http://ir.librarynmu.com/handle/123456789/6904 2021-01-01T00:00:00Z http://ir.librarynmu.com/handle/123456789/6639 Название: Взаємозв’язки показників добового моніторування артеріального тиску та інсулінорезистентності у дітей з метаболічним синдромом у м. Київ Авторы: Соловей, І. В.; Альюсеф, М. Х.; Гнилоскуренко, А. В. Sun, 01 Jan 2023 00:00:00 GMT http://ir.librarynmu.com/handle/123456789/6639 2023-01-01T00:00:00Z