http://ir.librarynmu.com/handle/123456789/18044 Wed, 12 Aug 2026 04:46:55 GMT 2026-08-12T04:46:55Z http://ir.librarynmu.com/handle/123456789/19899 Название: Surgical clinic for the treatment of tuberculous exudative pleurisy: availability of anti-tuberculosis medicines Авторы: Shapovalova, V.; Dovzhuk, V.; Dovzhuk, N. Краткий осмотр (реферат): Introduction. Tuberculous exudative pleurisy remains a complex clinical problem for surgical practice, especially in wartime, logistical disorders, and limited access to medicines. The peculiarities of the course of the disease, difficulties in diagnosis, and the need for invasive verification methods cause delays in diagnosis and treatment. The effectiveness of pharmacotherapy largely depends not only on the pharmacological properties of anti-tuberculosis drugs, but also on the stability of their availability in the pharmaceutical market. Purpose. To assess the availability of anti-tuberculosis drugs in Ukraine's pharmaceutical market using clinical content analysis technology, to ensure continuous pharmacotherapy for patients with tuberculous exudative pleurisy in surgical clinics. Materials and methods. The study was conducted from 2022 to 2026. The object of the study was anti-tuberculosis drugs in circulation in Ukraine. Clinical content analysis technology, based on the principles of evidence-based medicine, evidence-based pharmacy, and clinical and pharmacological analysis, was used. data processing (Sturgess formula), as well as regulatory, documentary, marketing, and graphic research methods. Results. The presence of 41 names of anti-tuberculosis drugs on the pharmaceutical market of Ukraine has been established. 4 groups of manufacturers have been identified based on the breadth of their range and the stability of their supply. It has been found that most drugs have confirmed quality of production (GMP) and bioequivalence, but there are some gaps in the availability of fixed combinations and pediatric forms. It has been proven that the continuity of pharmacotherapy depends on the availability of alternative manufacturers, the variety of dosage forms, and the stability of supply. Discussion. Content analysis as an innovative tool allows you to systematize information about medicines and relate it to clinical needs. The results obtained emphasize the importance of organizational support of treatment, including the formation of formularies, procurement planning, and ensuring the continuity of therapy. Particular attention should be paid to the risk of pharmacokinetic alterations associated with pleural localization, which may affect treatment effectiveness. Conclusions. Clinical technology of content analysis is an effective tool for assessing the availability of anti- tuberculosis drugs and optimizing pharmacotherapy for tuberculous exudative pleurisy. The need to provide at least two alternative manufacturers for each active ingredient and the availability of fixed combinations to increase adherence to treatment and prevent interruption of therapy have been determined. forms and procurement planning in health care institutions. Thu, 01 Jan 2026 00:00:00 GMT http://ir.librarynmu.com/handle/123456789/19899 2026-01-01T00:00:00Z http://ir.librarynmu.com/handle/123456789/19880 Название: The Role Of Early-Life Microbiota Programming And Age-Related Neuroendocrine Homeostasis Remodeling In The Modulation Of Cognitive Aging Авторы: Rusalov, V.; Lagodych, T.; Lukianenkom, I.; Lazarеnko, V. Краткий осмотр (реферат): The role of early life microbiome programming and age related neuroendocrine homeostasis remodeling in the development of cognitive aging is considered. Current data on the influence of the gut brain axis, intestinal microbiota, neuroinflammation, insulin resistance, and hormonal changes on neuroplasticity, the functional state of the central nervous system, and the development of neurodegenerative processes are summarized. It is shown that early dysbiosis, impairment of the intestinal barrier function, chronic low grade systemic inflammation, and age related deficiency of neuroprotective hormones may represent important factors contributing to cognitive decline and the acceleration of neurodegenerative changes during aging. Thu, 01 Jan 2026 00:00:00 GMT http://ir.librarynmu.com/handle/123456789/19880 2026-01-01T00:00:00Z http://ir.librarynmu.com/handle/123456789/19843 Название: The Relationship Between Regular Physical Activity And Cognitive Functions In Higher Education Students Авторы: Dovzhuk, N.; Bobrova, I. Краткий осмотр (реферат): Cognitive functions, including memory, thinking, and decision-making, are essential factors in the educational process, with attention playing a particularly important role in academic performance. Under conditions of increasing information overload, high levels of psycho-emotional stress, and the widespread prevalence of sedentary lifestyles, maintaining cognitive health has become especially important. Thu, 01 Jan 2026 00:00:00 GMT http://ir.librarynmu.com/handle/123456789/19843 2026-01-01T00:00:00Z http://ir.librarynmu.com/handle/123456789/19798 Название: Мікробіом кишечника як модифікатор когнітивних функцій та когнітивного старіння Авторы: Русалов, В. Л.; Лагодич, Т. С. Краткий осмотр (реферат): У статті узагальнено сучасні дані щодо ролі мікробіому кишечника як важливого модифікатора когнітивних функцій та процесів когнітивного старіння. Розглянуто основні механізми взаємодії в межах осі «кишечник–мозок», яка забезпечує двоспрямований зв’язок між центральною нервовою системою та кишковою мікробіотою через нейронні, імунні, ендокринні та метаболічні шляхи регуляції. Показано, що зміни складу мікробіоти можуть впливати на пам’ять, навчання, емоційний стан, нейропластичність і швидкість когнітивного спаду. Thu, 01 Jan 2026 00:00:00 GMT http://ir.librarynmu.com/handle/123456789/19798 2026-01-01T00:00:00Z